
产品货号:
Z34623
中文名称:
Ms CD8A Purified抗体
英文名称:
Anti-Ms CD8A Purified Antibody (Clone#53-6.7)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Ms CD8A Purified Antibody (Clone#53-6.7) |
指标别名 | CD8;CD8A;CD8a molecule;Leu2;MAL;p32 |
克隆性 | Monoclonal |
检验物种 | mouse |
应用范围 | FCM,IP,IHC,IHC-F,ICC |
基因名称 | CD8A |
克隆号 | 53-6.7 |
抗体来源 | Rat |
免疫原 | Murine spleen cells.The rat monoclonal antibody 53-6.7 recognizes an extracellular epitope of murine CD8a (32~34kDa;alpha chain of the CD8 antigen). |
计算分子量 | 27kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-G affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | The CD8a (CD8 alpha) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells,intraepithelial lymphocytes,NK cells,macrophages and dendritic cells.Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function.Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts.Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8,thereby affecting the functional diversity of the TCR signaling. |
Uniprot ID | P01731 |
基因名全称 | CD8a molecule |
蛋白名全称 | T-cell surface glycoprotein CD8 alpha chain |
推荐稀释比 | Flow cytometry:1.5μg/mL. Immunohistochemistry (frozen sections):1:1000;formaldehyde fixation is not recommended,acetone fixation is preferred. |
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